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KMID : 0981820100300020166
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Korean Journal of Laboratory Medicine
2010 Volume.30 No. 2 p.166 ~ p.170
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Disseminated Mycobacterium avium Complex Infection in a Non-HIV-infected Patient Undergoing Continuous Ambulatory Peritoneal Dialysis
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Chung Jin-Won
Cha Young-Joo
Oh Dong-Jin
Nam Woo-Jin
Kim Su-Hyun
Lee Mi-Kyung
Kim Hye-Ryun
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Abstract
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Isolated bone marrow infection by nontuberculous mycobacteria (NTM) is extremely rare. Recently, we encountered a case of bone marrow Mycobacterium avium complex (MAC) infection, which presented as a fever of unknown origin shortly after starting continuous ambulatory peritoneal dialysis (CAPD). The patient was diagnosed with MAC infection on the basis of PCR-restriction fragment length polymorphism analysis and sequencing of DNA obtained from bone marrow specimens. Although this was a case of severe MAC infection, there was no evidence of infection of other organs. End-stage renal disease (ESRD) patients undergoing dialysis can be considered immunodeficient; therefore, when these patients present with fever of unknown origin, opportunistic infections such as NTM infection should be considered in the differential diagnosis. (Korean J Lab Med 2010;30:166-70)
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KEYWORD
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End-stage renal disease, Mycobacterium avium complex, Bone marrow
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